MedWorm: Benztropine

  Benztropine

is a drug used to treat symptoms of Parkinson's disease and secondary parkinsonism. More... (Source: About.com Bipolar Disorder)

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  BENZTROPINE MESYLATEtablet [Rising Pharmaceuticals Inc]

Updated Date: Feb 24, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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  BENZTROPINE MESYLATEtablet [American Health Packaging]

Updated Date: Jan 19, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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  BENZTROPINE MESYLATEtablet [Pliva Inc.]

Updated Date: Dec 2, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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  BENZTROPINE MESYLATEtablet [UDL Laboratories, Inc.]

Updated Date: Nov 19, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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  BENZTROPINE MESYLATEinjection [West-Ward Pharmaceutical Corp]

Updated Date: Sep 22, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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  A dopamine transport inhibitor with markedly low abuse liability suppresses cocaine self-administration in the rat

Conclusions  These findings demonstrate essential psychopharmacological differences between AHN-1055 and cocaine and highlight important properties of the analog as a possible pharmacotherapy in cocaine addiction. Content Type Journal ArticleCategory Original InvestigationDOI 10.1007/s00213-009-1653-xAuthors Antonio Ferragud, University of Valencia-General Foundation & Red de Trastornos Adictivos (RETICS) Biopsychology and Comparative Neuroscience Group, Cavanilles Institute (ICBiBE) Polígono de la Coma s/n, Paterna 46980 Valencia SpainClara Velázquez-Sánchez, University of Valencia-General Foundation & Red de Trastornos Adictivos (RETICS) Biopsychology and Comparative Neuroscience Group, Cavanilles Institute (ICBiBE) Polígono de la Coma s/n, Paterna 46980 Valencia ...

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  What Are The Options for Treating Excessive Salivation?

Discussion Drooling, excessive salivation, hypersalivation, or sialorrhea can be a big problem for children. It can cause wet clothing necessitating bibs or multiple changes of clothing. It can cause dermatitis of the face, neck and chest, with possible skin breakdown and/or possible secondary infection. Sialorrhea can also potentiate the spread of common infections to others though direct or indirect contact with the saliva. It can also cause impaired social interaction as noted above. Therefore it is a problem that should be taken seriously and treated as necessary. Sialorrhea is generally considered abnormal if it occurs during the day after the age of 3-4 years. Most people affected have some other neurological problem including cerebral palsy or in adult populations, patients with Pa...

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  BENZTROPINE MESYLATEinjection, Solution [Hikma Farmaceutica]

Updated Date: Sep 4, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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  BENZTROPINE MESYLATEinjection [Nexus Pharmaceuticals Inc]

Updated Date: Aug 13, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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  BENZTROPINE MESYLATEtablet [Actavis Totowa LLC]

Updated Date: Jun 23, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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  Cogentin Side Effects

Catalogue of side effects for the medication Benztropine - brand name Cogentin - which is used to treat some of the side effects of certain antipsychotic medications. It is classed as an antiparkinsonian drug. (Source: About.com Bipolar Disorder)

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  [Articles] Double-Blind Comparison of First- and Second-Generation Antipsychotics in Early-Onset Schizophrenia and Schizo-affective Disorder: Findings From the Treatment of Early-Onset Schizophrenia Spectrum Disorders (TEOSS) Study

CONCLUSIONS: Risperidone and olanzapine did not demonstrate superior efficacy over molindone for treating early-onset schizophrenia and schizoaffective disorder. Adverse effects were frequent but differed among medications. The results question the nearly exclusive use of second-generation antipsychotics to treat early-onset schizophrenia and schizoaffective disorder. The safety findings related to weight gain and metabolic problems raise important public health concerns, given the widespread use of second-generation antipsychotics in youth for nonpsychotic disorders. (Source: Am J Psychiatry)

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  Double-Blind Comparison of First- and Second-Generation Antipsychotics in Early-Onset Schizophrenia and Schizo-affective Disorder: Findings From the Treatment of Early-Onset Schizophrenia Spectrum Disorders (TEOSS) Study.

Conclusions Risperidone and olanzapine did not demonstrate superior efficacy over molindone for treating early-onset schizophrenia and schizoaffective disorder. Adverse effects were frequent but differed among medications. The results question the nearly exclusive use of second-generation antipsychotics to treat early-onset schizophrenia and schizoaffective disorder. The safety findings related to weight gain and metabolic problems raise important public health concerns, given the widespread use of second-generation antipsychotics in youth for nonpsychotic disorders. PMID: 18794207 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)

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  Interaction of cocaine-, benztropine-, and gbr12909-like compounds with wildtype and mutant human dopamine transporters: molecular features that differentially determine antagonist binding properties.

This study furthers the concept of using DAT mutants to differentiate cocaine-like inhibitors from atypical inhibitors in vitro. Further studies of the molecular features that define inhibitor-transporter interaction could lead to the development of DAT inhibitors with differential clinical utility. PMID: 18786172 [PubMed - as supplied by publisher] (Source: Journal of Neurochemistry)

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  Benztropine Mesylate(Benztropine Mesylate) Tablet [UPSHER-SMITH LABORATORIES, INC.]

Updated Date: Mar 19, 2008 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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  Benztropine-induced Esotropia and Mydriasis.

Page: 312DOI: 10.1097/WNO.0b013e31815bfb04Authors: Oh, Sun-Young MD 1; Shin, Byoung-Soo MD 1; Lee, Yeon-Hee MD 2; Lee, Ae Young MD 3; Kim, Ji Soo MD 4 (Source: Journal of Neuro-Ophthalmology)

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  Azacitidine-Associated Hyperthermia and Interstitial Pneumonitis in a Patient with Myelodysplastic Syndrome

We describe a 55-year-old woman who was treated with azacitidine for myelodysplastic syndrome and experienced hyperthermia that was not attributable to other causes. The patient's treatment course was further complicated by interstitial pneumonitis and hypoxic respiratory failure that ultimately led to acute respiratory distress syndrome. Hyperthermia develops when discord occurs between metabolic heat production and heat dissipation. The process of temperature regulation can be altered by drugs such as succinylcholine, phenothiazines, monoamine oxidase inhibitors, atropine, benztropine, antihistamines, cocaine, Ecstasy, amphetamines, and haloperidol. The hyperthermia in this patient was refractory to antipyretic therapy and was not due to other drug-induced hyperthermic syndromes. She eve...

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  Fatal exertional heat stroke in a patient receiving zuclopenthixol, quetiapine and benztropine.

Authors: Kao RL, Kelly LM Objective To report a case of fatal exertional heat stroke associated with the use of zuclopenthixol, quetiapine and benztropine. Case Summary A 36-year-old male with a history of schizophrenia and bipolar disease was working as a roofer during the third day of a heat wave. His medications included zuclopenthixol, quetiapine, benztropine, carbamazepine and levothyroxine. He developed loss of consciousness late in the day and presented to hospital with a Glasgow Coma Scale 3 and a rectal temperature of 42.20C. He progressed to severe multiple organ dysfunction and asystole, and expired the following morning. Neuroleptic and anticholinergic agents have long been associated with heat alteration, but there are few reports involving the newer antipsychotic agents. ...

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  Role of calcium-independent phospholipase A2 in cortex striatum thalamus cortex circuitry–enzyme inhibition causes vacuous chewing movements in rats

Conclusions  These results suggest an important role for iPLA2 in the cortex–striatum–thalamus–cortex circuitry. It is postulated that VCM induced by iPLA2 inhibition may be a model of human parkinsonian tremor. Content TypeJournal Article JournalPsychopharmacologyOnline ISSN 1432-2072Print ISSN 0033-3158 (Source: Psychopharmacology)

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  Benztropine Mesylate(BENZTROPINE MESYLATE) Tablet [COREPHARMA LLC.]

Updated Date: Jun 29, 2007 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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  Benztropine pretreatment does not affect responses to acute cocaine administration in human volunteers

This study of one of the tropane-ring analogs that is approved for human use suggests this compound does not alter cocaine-induced effects, but just as importantly, does not produce any adverse behavioral or physiological effects. The exact therapeutic application of benztropine as a possible adjunct treatment for cocaine abuse in humans require further exploration. Copyright © 2006 John Wiley & Sons, Ltd. (Source: Human Psychopharmacology: Clinical and Experimental)

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  Review: Dystonia

This article discusses the following: • Clinical Features • Classification (Primary dystonia, primary generalised torsion dystonia, primary focal dystonia, secondary dystonia, heredodegenerative disorders, drug-induced dystonia, acquired structural lesions, dystonia-plus syndromes, paroxysmal dystonia). • Pathophysiology • Evaluation • Treatment (pharmacotherapy, botulinum toxin, surgery, physical therapies) The article notes that acute drug-induced dystonia can be caused by levodopa, dopamine agonists, antipsychotic drugs, anticonvulsant agents, SSRIs, and rarely by other miscellaneous drugs. In addition, persistent tardive dystonia may occur after prolonged use of dopamine-receptor–blocking antipsychotic drugs and metoclopramide. It may also occur as a result of the toxi...

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  Gain of function mutants reveal sites important for the interaction of the atypical inhibitors benztropine and bupropion with monoamine transporters

Journal of Neurochemistry Volume 0, Issue 0, Page ???-???. (Source: Journal of Neurochemistry)

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  Levomepromazine versus chlorpromazine in treatment-resistant schizophrenia: a double-blind randomized trial.

CONCLUSION: LMP and CPZ may be useful in the management of TRS. A modest advantage of LMP compared with CPZ was seen in longitudinal analysis. High doses of neuroleptics may contribute to TRS; reduction of neuroleptics to modest or moderate doses should be considered before categorizing a patient as treatment resistant. PMID: 16862245 [PubMed - as supplied by publisher] (Source: J Psychiatry Neurosc...)

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